Influence of Cholesterol Concentration on Bacteriorhodopsin Photocycle

Authors

  • L. A. Bulavin Taras Shevchenko National University of Kyiv
  • A. E. Mikhailov Moscow Institute of Physics and Technology
  • P. K. Kuzmichev Moscow Institute of Physics and Technology
  • V. V. Chupin Moscow Institute of Physics and Technology
  • V. I. Borshchevskiy Moscow Institute of Physics and Technology
  • I. V. Chizhov Medizinische Hochschule Hannover
  • D. V. Soloviov Moscow Institute of Physics and Technology, Institute for Safety Problems of Nuclear Power Plants, Nat. Acad. of Sci. of Ukraine, Joint Institute for Nuclear Research

DOI:

https://doi.org/10.15407/ujpe65.9.778

Keywords:

laser photolysis, lipid membranes, photocycle, bacteriorhodopsin, cholesterol

Abstract

The photocycle of the membrane protein bacteriorhodopsin in Dipalmitoylphosphatidylcholine(DPPC)/Cholesterol membranes with various cholesterol concentrations has been studied using the time-resolved spectroscopy method. The temperature dependences of the rate constants of bacteriorhodopsin transitions between transient states are shown to satisfy the Eyring equation. It is proved that the growth of the cholesterol concentration in the DPPC membrane accelerates the bacteriorhodopsin photocycle.

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Published

2020-08-26

How to Cite

Bulavin, L. A., Mikhailov, A. E., Kuzmichev, P. K., Chupin, V. V., Borshchevskiy, V. I., Chizhov, I. V., & Soloviov, D. V. (2020). Influence of Cholesterol Concentration on Bacteriorhodopsin Photocycle. Ukrainian Journal of Physics, 65(9), 778. https://doi.org/10.15407/ujpe65.9.778

Issue

Section

Physics of liquids and liquid systems, biophysics and medical physics

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