Model of Postsynaptic Membrane Deactivation

  • A. N. Vasilev Taras Shevchenko National University of Kyiv, Faculty of Physics, Chair of Theoretical Physics
  • O. V. Kulish Taras Shevchenko National University of Kyiv, Faculty of Physics, Chair of Theoretical Physics
Keywords: nerve impulse, synapse, mediator, receptor, postsynaptic membrane


A model has been proposed to describe the deactivation of a postsynaptic membrane after its excitation by transmitting a nerve impulse across the synapse. In particular, the process of mediator release in the form of choline from the postsynaptic membrane and its diffusive excretion from the synaptic cleft are considered. The time dependence of the number of activated receptors, the dependence of the maximum number of activated receptors on the activation time, and the space-time distribution of the choline concentration in the synaptic cleft are calculated.


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How to Cite
Vasilev, A., & Kulish, O. (2018). Model of Postsynaptic Membrane Deactivation. Ukrainian Journal of Physics, 63(10), 919.
Physics of liquids and liquid systems, biophysics and medical physics