Influence of Cholesterol Concentration on Bacteriorhodopsin Photocycle

  • L. A. Bulavin Taras Shevchenko National University of Kyiv
  • A. E. Mikhailov Moscow Institute of Physics and Technology
  • P. K. Kuzmichev Moscow Institute of Physics and Technology
  • V. V. Chupin Moscow Institute of Physics and Technology
  • V. I. Borshchevskiy Moscow Institute of Physics and Technology
  • I. V. Chizhov Medizinische Hochschule Hannover
  • D. V. Soloviov Moscow Institute of Physics and Technology, Institute for Safety Problems of Nuclear Power Plants, Nat. Acad. of Sci. of Ukraine, Joint Institute for Nuclear Research
Keywords: laser photolysis, lipid membranes, photocycle, bacteriorhodopsin, cholesterol


The photocycle of the membrane protein bacteriorhodopsin in Dipalmitoylphosphatidylcholine(DPPC)/Cholesterol membranes with various cholesterol concentrations has been studied using the time-resolved spectroscopy method. The temperature dependences of the rate constants of bacteriorhodopsin transitions between transient states are shown to satisfy the Eyring equation. It is proved that the growth of the cholesterol concentration in the DPPC membrane accelerates the bacteriorhodopsin photocycle.


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How to Cite
Bulavin, L., Mikhailov, A., Kuzmichev, P., Chupin, V., Borshchevskiy, V., Chizhov, I., & Soloviov, D. (2020). Influence of Cholesterol Concentration on Bacteriorhodopsin Photocycle. Ukrainian Journal of Physics, 65(9), 778.
Physics of liquids and liquid systems, biophysics and medical physics

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