Two-Photon Exchange in Elastic Electron Scattering on Hadronic Systems
DOI:
https://doi.org/10.15407/ujpe67.1.80Keywords:
SERS substrates, Raman spectroscopy, R6G, biomoleculesAbstract
A possibility of creating universal and effective SERS substrates via controlled aggregation of gold and silver colloidal nanoparticles (NPs) on substrates with a specially developed surface morphology has been demonstrated. Unlike the previous work on the development and research of SERS substrates, in which the enhancement was mainly realized on separate protruding nanoparticles or nanoislands, the change to the multilevel substrate structuring and the controlled aggregation of the deposited colloidal plasmonic NPs substantially increases the formation probability of hot spots and getting analyte molecules onto them. The efficiency of the proposed approach has been demonstrated for several organic analytes of various types, in particular, the R6G dye, the cysteine amino acid, and antibodies.
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