Hydrogel-Silver Nanoparticle Composites for Biomedical Applications

  • O. Nadtoka Taras Shevchenko National University of Kyiv
  • N. Kutsevol Taras Shevchenko National University of Kyiv
  • T. Bezugla Taras Shevchenko National University of Kyiv
  • P. Virych Taras Shevchenko National University of Kyiv
  • A. Naumenko Taras Shevchenko National University of Kyiv
Keywords: silver nanoparticles, hydrogel, polyacrylamide, TEM, FTIR, UV–Vis spectroscopy

Abstract

Polyacrylamide and dextran-graft-polyacrylamide hydrogels are prepared and used as nanoreactors and networks for the synthesis of silver nanoparticles (AgNPs). Photochemical generation of AgNPs is carried out under UV-irradiation of Ag+ ions in swollen hydrogels of different cross-linking densities. The obtained hydrogels and hydrogel/AgNPs composites are characterized by TEM, FTIR, and UV–Vis spectroscopy. Swelling studies have shown a relationship between the structure of the hydrogels and their ability to swell. It is shown that the presence of AgNPs in the polymer network leads to a decrease of the swelling capacity. An increase in the cross-linking density leads to an expansion of the AgNPs size distribution for both types of hydrogels. All synthesized hydrogel-silver nanoparticle composites have shown a high activity in the growth retardation of Staphylococcus aureus microorganisms.

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Published
2020-05-11
How to Cite
Nadtoka, O., Kutsevol, N., Bezugla, T., Virych, P., & Naumenko, A. (2020). Hydrogel-Silver Nanoparticle Composites for Biomedical Applications. Ukrainian Journal of Physics, 65(5), 446. https://doi.org/10.15407/ujpe65.5.446
Section
Physics of liquids and liquid systems, biophysics and medical physics