On the Velocity of Enzymatic Reactions in Michaelis–Menten-Like Schemes (Ensemble and Single-Molecule Versions)

  • L. N. Christophorov Bogolyubov Institute for Theoretical Physics, Natl. Acad. Sci. Ukraine
Keywords: enzymatic reactions, Michaelis–Menten schemes, monomeric enzymes, conformational regulation, reaction velocity

Abstract

In searching non-standard ways of conformational regulation, various Michaelis–Menten-like schemes attract relentless attention, resulting in sometimes too sophisticated considerations. With the example of monomeric enzymes possessing an only binding site, we define the minimal schemes capable of bearing peculiar regulatory properties like “cooperativity” or substrate inhibition. The simplest ways of calculating the enzymatic reaction velocity are exemplified, either in the ensemble or single-molecule case.

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Published
2020-05-11
How to Cite
Christophorov, L. (2020). On the Velocity of Enzymatic Reactions in Michaelis–Menten-Like Schemes (Ensemble and Single-Molecule Versions). Ukrainian Journal of Physics, 65(5), 412. https://doi.org/10.15407/ujpe65.5.412
Section
Physics of liquids and liquid systems, biophysics and medical physics