Small-Angle X-Ray Scattering And Differential Scanning Calorimetry Studies of DPPC Multilamellar Structures Containing Membranotropic Agents of Different Chemical Nature

  • L. A. Bulavin Taras Shevchenko National University of Kyiv, Institute for Safety Problems of Nuclear Power Plants, Nat. Acad. of Sci. of Ukraine
  • D. V. Soloviov Institute for Safety Problems of Nuclear Power Plants, Nat. Acad. of Sci. of Ukraine, Joint Institute for Nuclear Research, Moscow Institute of Physics and Technology
  • A. I. Kuklin Joint Institute for Nuclear Research, Moscow Institute of Physics and Technology
  • L. N. Lisetski Institute for Scintillation Materials, Nat. Acad. of Sci. of Ukraine
  • N. A. Kasian Institute for Scintillation Materials, Nat. Acad. of Sci. of Ukraine
  • A. O. Krasnikova Institute for Scintillation Materials, Nat. Acad. of Sci. of Ukraine
  • O. V. Vashchenko Institute for Scintillation Materials, Nat. Acad. of Sci. of Ukraine
  • A. V. Zinchenko Institute for Problems of Cryobiology and Cryomedicine, Nat. Acad. of Sci. of Ukraine
Keywords: small-angle X-ray scattering, membranotropic agents, liquid crystal, dipalmitoylphosphatidylcholine

Abstract

Multilamellar structures formed in DPPC/water/glycerol and DPPC/water/oxyethylated glycerol systems are studied by small-angle X-ray scattering (SAXS) and differential scanning calorimetry (DSC) methods. The effects of glycerol, oxyethylated glycerol, and other membranotropic agents (MTAs) on the lamellar repeat distance D are compared in gel, ripple, and high-temperature (La) liquid crystal phases of the hydrated phospholipids. It is noted that the introduction of MTAs could lead to different types of ‘D vs. temperature’ behavior in the La phase, which is correlated with changes in D caused by the introduction of these substances to the DPPC/water reference system.

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Published
2019-01-15
How to Cite
Bulavin, L., Soloviov, D., Kuklin, A., Lisetski, L., Kasian, N., Krasnikova, A., Vashchenko, O., & Zinchenko, A. (2019). Small-Angle X-Ray Scattering And Differential Scanning Calorimetry Studies of DPPC Multilamellar Structures Containing Membranotropic Agents of Different Chemical Nature. Ukrainian Journal of Physics, 60(9), 905. https://doi.org/10.15407/ujpe60.09.0905
Section
Solid matter