Modeling the Impulse Transmission through a System of Two Synapses
DOI:
https://doi.org/10.15407/ujpe71.3.236Keywords:
impulse, synapse, mediator, membrane, receptor, activationAbstract
A model describing the process of nerve signal transmission through a system consisting of two interacting synapses has been proposed. The model is based on nonlinear differential equations that describe the activation of receptors on the postsynaptic membranes of two synaptic clefts. The interaction between the synapses is implemented in such a way that the activation of receptors on the first postsynaptic membrane determines the intensity of mediator injection into the second synapse. The peculiarities of the stationary state of this system have been studied, and the stability of this state has been shown. The influence of the intensity of mediator injection into the first synapse of the system on the concentration of activated receptors in the second synapse has also been analyzed. It has been demonstrated that the reliability of the entire system is not violated at a qualitative level, and the character of the receptor activation process on the postsynaptic membrane of the second synapse remains stable with respect to variations in the input signal.
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